Nasopharyngeal Carcinoma: Imaging Diagnosis and Recent Progress
With continuous development of imaging techniques, medical imaging plays an important role in diagnosis of Nasopharyngeal Carcinoma (NPC). Computed tomography (CT) is the basic mean for diagnosis of NPC and has an advantage over diagnosis of those involving the skull base. Magnetic resonance imaging(MRI) has an excellent soft tissue contrast resolution and it is superior to CT for detecting areas involving early primary focal invasion and retropharyngeal lymph node metastasis. With positron emission tomography(PET) imaging alone, the anatomical localization is unclear but when combined with CT, it shows high sensitivity in the identification of primary tumor, lymph node metastasis and distant metastasis. In this article, we review the current imaging methods commonly used in clinical diagnosis of nasopharyngeal carcinoma and discuss the most recent advances.
Zheng GL, Zeng QX, Wu PH, et al. Computed tomography in the management of nasopharyngeal carcinoma. Clini Radiol 1989; 40: 25.
Liu YL, Chen X, Chen J, et al. Nasopharyngeal carcinoma CT perfusion imaging and their correlation in biology study. Chin J Radiol 2007;41( 9) : 907- 9111.
Song YG, Liu JH, Zhao GM, et al. Curved planar reform ation and anatomical study. Journal of Practical Radiology, 2006, 22( 12) :1441-51
Sun Y, Mao YP, Ma J, et al. The role of MRI in nasopharyngeal cancer staging［J］. Chinese Journal of Cancer 2007;26(2):158-63.
Cheng YZ, Hu CS, Zhou ZR, et al. The bone of the skull base invasion of nasopharyngeal carcinoma (NPC) CT and MRI contrast detection [J]. China Oncology 2005; 15( 2) :167-8.
Takahara T, Imai Y, Yamashita T, et al. Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med 2004;22(4):275-82.
Fong D, Bhatia KS, Yeung D, et al. Diagnostic accuracy of diffusion-weighted MR imaging for nasopharyngeal carcinoma, head and neck lymphoma and squamous cell carcinoma at the primary site. Oral Oncol 2010;46:603-6.
Ozgen B, Oguz KK, Cila A. Diffusion MR imaging features of skull base osteomyelitis compared with skull base malignancy[J]. AJNR Am J Neuroradiol. 2011;32:179-84.
Chawla S, Kim S, Loevner LA, et al. Proton and phosphorous MR spectroscopy in squamous cell carcinomas of the head and neck. Acad Radiol. 2009;16:1366-72.
Jansen JF, Sch der H, Lee NY. Tumor metabolism and perfusion in head and neck squamous cell carcinoma : pretreatment multimodality imaging with 1H magnetic resonance spectroscopy,dynamic contrast-enhanced MRI, and [18F]FDG-PET [J]. Int J Radiat Oncol Biol Phys 2012;1;82:299-307.
Li H, Li JP, Lin CG, et al. An experimental study on acute brain radiation injury: Dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology. Eur J Radiol 2012;81(11):3496-503.
Quon H, Brizel DM. Predictive and prognostic role of functional imaging of head and neck squamous cell carcinomas. Semin Radiat Oncol 2012;22(3):220-32.
Chapman CH, Nagesh V, Sundgren PC. Diffusion tensor imaging of normal-appearing white matter as biomarker for radiation-induced late delayed cognitive decline[J]. Int J Radiat Oncol Biol Phys 2012;82:2033-40.
Teo P, Lee WY, Yu P. The prognostic significance of parapharyngeal tumor involvement in nasopharyngeal carcinoma. Radio therOncol 1996;39:209-21.
Chong VF, Mukherji SK, Ng SH, et al. Nasopharyngeal carcinoma ：review of how imaging affects staging. J Comput Assist Tomogr 1999;23(6):984-993.
Chen YB, Fang YH, Chen Y, et al. MRI study on the relationship between the invasion patterns and staging of nasopharyngeal carcinoma. Chinese Journal of Radiology 2010;44(10):1024-9.
CHENG SH, TSAI SY, HORNG CF, et al. A prognostic scoring system for locoregional control in nasopharyngeal carcinoma following conformal radiotherapy［J]. Int J Radiat Oncol Biol Phys 2006;66:992-1003.
Galloway TJ, Morris CG, Mancuso AA, et al. Impact of radiographic findings on prognosis for skin carcinoma with clinical perineural invasion. Cancer 2005;103(6): 1254-7.
Liu L, Liang S, Li L, et al. Prognostic impact of magnetic resonnce I maging-detected cranial nerve involvement in nasopharyngeal carcinoma. Cancer 2009;115:1995-2003.
King AD, Ahuja AT, Leung SF, et al. Neck node metastases from nasopharyngeal carcinoma：MR imaging of patterns of disease[J]. Head Neck 2000;22(3):275-81.
Lam WW, Chan YL, Leung SF, et al. Retropharyngeal lymphadenophy in nasopharyngeal carcinoma[J]. Head Neck 1997;19(3):76-181.
ChangMC,ChenJH,LiangJA,etal. Accuracyof whole-body FDG-PET and FDG-PET/CT in M staging of nasopharyngeal carcinoma: a systematic review and meta-analysis. Eur J Radiol. 2013 Feb;82(2):366-73.
Liu T, Xu W, Yan WL, et al. FDG-PET，CT，MRI for diagnosis of local residual or recurrent nasopharyngeal carcinoma，which one is the best? A systematic review [J]. Radiother Oncol 2007;85(3): 327-35.
ANTOCH G, VOGT FM, FREUDENBERG LS, et al. Wholebody dual-modality PET/CT and whole-body MRI for tumor staging in oncology［J］. JAMA 2003; 290(24): 3199-3206. 25. Ng SH, Liu HM, Ko SF, et al. Posttreatment imaging of the nascopharynx. Eur J Radiol 2002;44(2):82-95.
LIU T, XU W, YAN WL. FDG-PET, CT, MRI for diagnosis of local residual or recurrent nasopharyngea carcinoma, which one is the best? A systematic review[J]. Radiother Oncol 2007;85(3): 327-35.
Ng SH, Joseph CT, Chan SC, et al. Clinical usefulness of 18FFDG PET in nasopharyngeal carcinoma patients with questionable MRI findings for recurrence. J Nucl Med,2004,45(10):1669-76.
Yen RF, Hung RL, Pan MH, et al. 18-fluoro-2-deoxyglucose positron emission tomography in detecting residual/recurrent nasopharyngeal carcinomas and comparison with magnetic resonance imaging. Cancer 2003;98(2):283-287.
TSA IM H, SH IAU Y C, KAO CH, et al. Detection of recurrent nasophryngeal carcinom asw ith positron em iss ion tomography using 18- fluoro- 2-deoxyglucose in pat ien tsw ith indeterm inatem agnetic reson ance im ag ing find ings after rad iotherapy[ J] . Cancer Res Clin Oncol 2002;128(5):279-82.
Kao CH, Chang Hanglaisp. Detection of recurrent or persistent nasopharyngeal carcinomas after radio therapy with 18-fluoro-2-deoxyglu cose positron emission tomography and comparison with computed tomography. Clin Oncol. 1998;16(11) : 3550-5.
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