Present status and advances in target delineation for intensity-modulated radiotherapy of nasopharyngeal carcinoma

Jin-Feng Rong


The treatment of nasopharyngeal carcinoma (NPC) has improved significantly owing to advances in radiation therapy, such as intensity-modulated radiotherapy (IMRT). However, the optimal delineation of the target area remains the subject of debate and continued study. Herein, we discuss the role of IMRT, and review recent studies demonstrating the benefits of decreasing clinical target volume according to the locoregional extension patterns of NPC as well as the benefits of target delineation on the basis of cervical fascia anatomy along with the benefits of replanning IMRT with neoadjuvant chemotherapy. Significant advances have been observed, and we anticipate further continued advances.

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